G2P2C RL architecture (PPO/SAC for glucose control) maps directly to RL for medication titration in treatment-resistant depression. Same control theory, different biomarker signal.

UNetPlusPlus (⭐2652) and PanTS segmentation architecture directly applicable to MS white matter lesion segmentation in brain MRI. Same transformer encoder-decoder topology, different anatomy.

iAPS closed-loop architecture (sensor → algorithm → actuator) could model autonomic dysfunction monitoring — HRV + CGM-like biosensors → algorithmic detection of post-exertional malaise onset.

Artificial-pancreas-simulator architecture (ODE-based physiological modeling, discrete event simulation) transfers to ALS motor neuron loss modeling. Auto-save gap (#3) would be critical to fix first.